How does gamma irradiation work?
High-energy photons are emitted from an isotope source (Cobalt 60) producing ionization (electron disruptions) throughout a product. In living cells, these disruptions result in damage to the DNA and other cellular structures. These photon-induced changes at the molecular level cause the death of the organism or render the organism incapable of reproduction. The gamma process does not create residuals or impart radioactivity in processed products.
What is gamma irradiation used for?
The gamma process can effectively sterilize a wide variety of products composed of different materials, with varying densities, configurations and orientations.
Gamma radiation sterilization is ideal for:
- Sterilization of single-use medical supplies such as syringes, implants, catheters, IV sets, surgical gloves, gauze and more
- Elimination of organisms from pharmaceuticals such as ointments and solutions
- Sterilization of tissue/biological based products
- Microbial reduction on consumer products
For a complete list of products commonly treated with gamma radiation, please see Technical Tip # 4
What is a typical gamma processing cycle?
- The product arrives on a truck and is unloaded at the processing facility
- The product is received by lot and product code that is entered into the STERIS Isomedix Operating Data Management System (ODMS) which provides for run generation, scheduling, processing, certification and release of product for shipment
- The product is loaded into the carrier/tote per established configurations, dosimeters are placed, and the product is exposed to the radiation field (Cobalt 60 source rack)
- Dosimeters are analyzed after irradiation of the product is complete, to confirm that the required dose has been delivered
- All documentation and processing history records are reviewed, and if they are acceptable and Customer specifications are met, the product is released and shipped for use or further distribution
Contact STERIS Isomedix to learn more about our gamma irradiation services.